{"id":198,"date":"2018-10-01T20:18:47","date_gmt":"2018-10-01T20:18:47","guid":{"rendered":"https:\/\/www-menarah-org.kentuniresestg.wpengine.com\/?p=198"},"modified":"2024-01-08T09:52:15","modified_gmt":"2024-01-08T09:52:15","slug":"sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice","status":"publish","type":"post","link":"https:\/\/menarah.org\/ar\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/","title":{"rendered":"\u062d\u062c\u0628 \u0633\u064a\u0631\u0646\u0627 \u0644\u0647\u062f\u0641 \u0627\u0644\u062b\u062f\u064a\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0631\u0627\u0628\u0627\u0645\u064a\u0633\u064a\u0646"},"content":{"rendered":"

\u0627\u0639\u062a\u0644\u0627\u0644 \u0627\u0644\u062a\u0627\u0648\u0648\u0628\u0627\u062b\u064a \u0647\u0648 \u0627\u0644\u0633\u0645\u0629 \u0627\u0644\u0645\u0631\u0636\u064a\u0629 \u0627\u0644\u0645\u0645\u064a\u0632\u0629 \u0644\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u062a\u0646\u0643\u0633\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629. \u0648\u064a\u062a\u0645\u064a\u0632 \u0628\u0645\u062c\u0627\u0645\u064a\u0639 \u063a\u064a\u0631 \u0637\u0628\u064a\u0639\u064a\u0629 \u0645\u0646 \u0627\u0644\u0641\u0648\u0633\u0641\u0648\u062a\u0627\u0648 \u0627\u0644\u0645\u0631\u0636\u064a \u0648\u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u062c\u0633\u062f\u064a. \u0625\u062d\u062f\u0649 \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0644\u0639\u0644\u0627\u062c \u0627\u0639\u062a\u0644\u0627\u0644 \u0627\u0644\u062a\u0627\u0648 \u0647\u064a \u062a\u062d\u0641\u064a\u0632 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0645 \u0627\u0644\u0630\u0627\u062a\u064a\u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u0627\u0644\u062a\u062e\u0644\u0635 \u0645\u0646 \u062a\u062c\u0645\u0639\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0645\u0631\u0636\u064a\u0629. \u0623\u062d\u062f \u0623\u062f\u0648\u0627\u062a \u0627\u0644\u062a\u062d\u0643\u0645 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0641\u064a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0645 \u0627\u0644\u0630\u0627\u062a\u064a \u0647\u0648 mTOR. \u0646\u0638\u0631\u064b\u0627 \u0644\u0623\u0646 \u062a\u062d\u0641\u064a\u0632 mTOR \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0645 \u0627\u0644\u0630\u0627\u062a\u064a\u060c \u0641\u0625\u0646 \u0645\u062b\u0628\u0637\u0627\u062a mTOR \u0633\u0648\u0641 \u062a\u0633\u0628\u0628 \u062a\u062d\u0641\u064a\u0632 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0645 \u0627\u0644\u0630\u0627\u062a\u064a. \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u062a\u0642\u0631\u064a\u0631\u060c \u062a\u0645 \u0625\u062d\u062f\u0627\u062b \u0627\u0639\u062a\u0644\u0627\u0644 \u0627\u0644\u062a\u0627\u0648\u0648\u0628\u0627\u062b\u064a \u0641\u064a \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0623\u0646\u0648\u0646\u0627\u0633\u064a\u0646. \u062a\u0645 \u062a\u062d\u0642\u064a\u0642 \u062d\u0638\u0631 mTOR \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062d\u0642\u0646 \u0627\u0644\u062a\u062c\u0633\u064a\u0645\u064a \u0644\u0640 siRNA \u0636\u062f mTOR. \u0643\u0634\u0641 \u0627\u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0633\u0644\u0648\u0643\u064a \u0648\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0639\u0646 \u062a\u0637\u0648\u0631 \u0646\u0645\u0648\u0630\u062c \u0627\u0639\u062a\u0644\u0627\u0644 \u0627\u0644\u062a\u0627\u0648\u0648\u0628\u0627\u062b\u064a \u0643\u0645\u0627 \u062b\u0628\u062a \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0623\u062f\u0627\u0621 \u0627\u0644\u0633\u0644\u0648\u0643\u064a \u0641\u064a \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0645\u062c\u0627\u0644 \u0627\u0644\u0645\u0641\u062a\u0648\u062d \u0648\u062a\u062c\u0645\u0639\u0627\u062a \u062a\u0627\u0648 \u0627\u0644\u0643\u0628\u064a\u0631\u0629 \u0641\u064a \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0628\u0627\u0644\u0623\u0646\u0627\u0633\u064a\u0646. \u0643\u0634\u0641 \u062d\u062c\u0628 mTOR \u0639\u0646 \u0625\u0632\u0627\u0644\u0629 \u0643\u0628\u064a\u0631\u0629 \u0644\u0645\u062c\u0627\u0645\u064a\u0639 \u062a\u0627\u0648 \u0641\u064a \u0627\u0644\u062c\u0627\u0646\u0628 \u0627\u0644\u0645\u062d\u0642\u0648\u0646\u061b \u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u0644\u0645 \u064a\u062a\u0623\u062b\u0631 \u062a\u0639\u0628\u064a\u0631 \u062a\u0627\u0648 \u0628\u0627\u0646\u0633\u062f\u0627\u062f mTOR.<\/p>\n\n\n\n

\u0633\u0644\u0627\u0645\u0629<\/strong> \u0645\u060c \u0627\u0644\u062f\u0633\u0648\u0642\u064a \u0633\u060c \u0627\u0644\u0633\u064a\u062f \u0623\u060c \u0627\u0644\u062d\u0633\u064a\u0646\u064a \u0645\u060c \u0639\u0628\u0627\u0633 \u0643\u060c \u0641\u0643\u0631\u064a \u0625\u060c \u0634\u0628\u0643\u0629 \u0623\u0648\u060c \u0627\u0644\u062e\u0636\u0631\u064a \u0633\u060c \u064a\u0648\u0633\u0641 \u0645\u060c \u0635\u0628\u062d \u0645\u060c \u0645\u062d\u0645\u062f \u0648. (2018). \u064a\u0624\u062f\u064a \u062d\u062c\u0628 \u0633\u064a\u0631\u0646\u0627 \u0644\u0647\u062f\u0641 \u0627\u0644\u062b\u062f\u064a\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0631\u0627\u0628\u0627\u0645\u0627\u064a\u0633\u064a\u0646 (mTOR) \u0625\u0644\u0649 \u062a\u062e\u0641\u064a\u0641 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0641\u064a \u0627\u0639\u062a\u0644\u0627\u0644 \u0627\u0644\u062a\u0627\u0648\u0648\u0628\u0627\u062b\u064a \u0627\u0644\u0646\u0627\u062c\u0645 \u0639\u0646 \u0627\u0644\u0623\u0646\u0648\u0646\u0627\u0633\u064a\u0646 \u0641\u064a \u0627\u0644\u0641\u0626\u0631\u0627\u0646.<\/a> \u0627\u0644\u062f\u0642\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629. <\/p>","protected":false},"excerpt":{"rendered":"

Tauopathy is a pathological hallmark of many neurodegenerative diseases. It is characterized by abnormal aggregates of pathological phosphotau and somatodendritic redistribution. One suggested strategy for treating tauopathy is to stimulate autophagy, hence, getting rid of these pathological protein aggregates. One key controller of autophagy is mTOR. Since stimulation of mTOR leads to inhibition of autophagy, […]<\/p>\n","protected":false},"author":13,"featured_media":282,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,17],"tags":[24,61,95],"class_list":{"0":"post-198","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-international_learning","8":"category-publications","9":"tag-24","10":"tag-health","11":"tag-research"},"yoast_head":"\nsiRNA blocking of mammalian target of rapamycin - Menarah<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/menarah.org\/ar\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/\" \/>\n<meta property=\"og:locale\" content=\"ar_AR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"siRNA blocking of mammalian target of rapamycin - Menarah\" \/>\n<meta property=\"og:description\" content=\"Tauopathy is a pathological hallmark of many neurodegenerative diseases. It is characterized by abnormal aggregates of pathological phosphotau and somatodendritic redistribution. One suggested strategy for treating tauopathy is to stimulate autophagy, hence, getting rid of these pathological protein aggregates. One key controller of autophagy is mTOR. Since stimulation of mTOR leads to inhibition of autophagy, […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/menarah.org\/ar\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/\" \/>\n<meta property=\"og:site_name\" content=\"Menarah\" \/>\n<meta property=\"article:published_time\" content=\"2018-10-01T20:18:47+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-08T09:52:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12.png\" \/>\n\t<meta property=\"og:image:width\" content=\"2468\" \/>\n\t<meta property=\"og:image:height\" content=\"1320\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Dr. Mohamed Salama\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u0643\u064f\u062a\u0628 \u0628\u0648\u0627\u0633\u0637\u0629\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dr. Mohamed Salama\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u0648\u0642\u062a \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0645\u064f\u0642\u062f\u0651\u0631\" \/>\n\t<meta name=\"twitter:data2\" content=\"\u062f\u0642\u064a\u0642\u0629 \u0648\u0627\u062d\u062f\u0629\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/\"},\"author\":{\"name\":\"Dr. Mohamed Salama\",\"@id\":\"https:\\\/\\\/menarah.org\\\/#\\\/schema\\\/person\\\/31d8b4616fa7455ebb0b07916a647a77\"},\"headline\":\"siRNA blocking of mammalian target of rapamycin\",\"datePublished\":\"2018-10-01T20:18:47+00:00\",\"dateModified\":\"2024-01-08T09:52:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/\"},\"wordCount\":188,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2018\\\/10\\\/Screenshot-2020-06-24-at-15.29.12.png\",\"keywords\":[\"2018\",\"Health\",\"Research\"],\"articleSection\":[\"Learning from the International Experience\",\"Publications\"],\"inLanguage\":\"ar\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/\",\"url\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/\",\"name\":\"siRNA blocking of mammalian target of rapamycin - Menarah\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2018\\\/10\\\/Screenshot-2020-06-24-at-15.29.12.png\",\"datePublished\":\"2018-10-01T20:18:47+00:00\",\"dateModified\":\"2024-01-08T09:52:15+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/#\\\/schema\\\/person\\\/31d8b4616fa7455ebb0b07916a647a77\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#breadcrumb\"},\"inLanguage\":\"ar\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ar\",\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#primaryimage\",\"url\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2018\\\/10\\\/Screenshot-2020-06-24-at-15.29.12.png\",\"contentUrl\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2018\\\/10\\\/Screenshot-2020-06-24-at-15.29.12.png\",\"width\":2468,\"height\":1320},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/menarah.org\\\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/menarah.org\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"siRNA blocking of mammalian target of rapamycin\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/menarah.org\\\/#website\",\"url\":\"https:\\\/\\\/menarah.org\\\/\",\"name\":\"Menarah\",\"description\":\"Middle East & North Africa Research on Ageing Healthy\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/menarah.org\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ar\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/menarah.org\\\/#\\\/schema\\\/person\\\/31d8b4616fa7455ebb0b07916a647a77\",\"name\":\"Dr. Mohamed Salama\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ar\",\"@id\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2020\\\/05\\\/M_Salama_photo-1.jpg\",\"url\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2020\\\/05\\\/M_Salama_photo-1.jpg\",\"contentUrl\":\"https:\\\/\\\/menarah.org\\\/wp-content\\\/uploads\\\/2020\\\/05\\\/M_Salama_photo-1.jpg\",\"caption\":\"Dr. Mohamed Salama\"},\"description\":\"Institute of Global Health and Human Ecology,\u00a0American University in Cairo, Egypt Dr Mohamed Salama established the first Translational Neuroscience Unit in Egypt. Mohamed\u2019s collaborative research led to establishing the Egyptian Network for Neurodegenerative Disorders (ENND). Mohamed was selected as a SOT Global Senior Scholar in 2013 and Translational\\\/bridging awardee in 2016. He was awarded by Parkinson\u2019s and Movement Disorders Foundation (PMDF) for his continuing research in the field of neurodegeneration. Recently, Mohamed and his colleagues succeeded to draft the first Reference Egyptian Genome\u00a0and collaborating with other colleagues to start a national cohort (A Longitudinal Study of Egyptian Health Aging [AL-SEHA]).\u00a0Currently, Mohamed is Atlantic senior fellow for Equity in brain health at the Global Brain Health Institute (GBHI) and Associate professor at the Institute of Global Health and Human Ecology at the American University in Cairo (AUC).\",\"url\":\"https:\\\/\\\/menarah.org\\\/ar\\\/author\\\/mohamedsalama\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u062d\u062c\u0628 \u0633\u064a\u0631\u0646\u0627 \u0644\u0647\u062f\u0641 \u0627\u0644\u062b\u062f\u064a\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0631\u0627\u0628\u0627\u0645\u064a\u0633\u064a\u0646 - \u0627\u0644\u0645\u0646\u0627\u0631\u0629","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/menarah.org\/ar\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/","og_locale":"ar_AR","og_type":"article","og_title":"siRNA blocking of mammalian target of rapamycin - Menarah","og_description":"Tauopathy is a pathological hallmark of many neurodegenerative diseases. It is characterized by abnormal aggregates of pathological phosphotau and somatodendritic redistribution. One suggested strategy for treating tauopathy is to stimulate autophagy, hence, getting rid of these pathological protein aggregates. One key controller of autophagy is mTOR. Since stimulation of mTOR leads to inhibition of autophagy, […]","og_url":"https:\/\/menarah.org\/ar\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/","og_site_name":"Menarah","article_published_time":"2018-10-01T20:18:47+00:00","article_modified_time":"2024-01-08T09:52:15+00:00","og_image":[{"width":2468,"height":1320,"url":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12.png","type":"image\/png"}],"author":"Dr. Mohamed Salama","twitter_card":"summary_large_image","twitter_misc":{"\u0643\u064f\u062a\u0628 \u0628\u0648\u0627\u0633\u0637\u0629":"Dr. Mohamed Salama","\u0648\u0642\u062a \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0645\u064f\u0642\u062f\u0651\u0631":"\u062f\u0642\u064a\u0642\u0629 \u0648\u0627\u062d\u062f\u0629"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#article","isPartOf":{"@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/"},"author":{"name":"Dr. Mohamed Salama","@id":"https:\/\/menarah.org\/#\/schema\/person\/31d8b4616fa7455ebb0b07916a647a77"},"headline":"siRNA blocking of mammalian target of rapamycin","datePublished":"2018-10-01T20:18:47+00:00","dateModified":"2024-01-08T09:52:15+00:00","mainEntityOfPage":{"@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/"},"wordCount":188,"commentCount":0,"image":{"@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#primaryimage"},"thumbnailUrl":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12.png","keywords":["2018","Health","Research"],"articleSection":["Learning from the International Experience","Publications"],"inLanguage":"ar","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/","url":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/","name":"\u062d\u062c\u0628 \u0633\u064a\u0631\u0646\u0627 \u0644\u0647\u062f\u0641 \u0627\u0644\u062b\u062f\u064a\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0631\u0627\u0628\u0627\u0645\u064a\u0633\u064a\u0646 - \u0627\u0644\u0645\u0646\u0627\u0631\u0629","isPartOf":{"@id":"https:\/\/menarah.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#primaryimage"},"image":{"@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#primaryimage"},"thumbnailUrl":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12.png","datePublished":"2018-10-01T20:18:47+00:00","dateModified":"2024-01-08T09:52:15+00:00","author":{"@id":"https:\/\/menarah.org\/#\/schema\/person\/31d8b4616fa7455ebb0b07916a647a77"},"breadcrumb":{"@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#breadcrumb"},"inLanguage":"ar","potentialAction":[{"@type":"ReadAction","target":["https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/"]}]},{"@type":"ImageObject","inLanguage":"ar","@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#primaryimage","url":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12.png","contentUrl":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12.png","width":2468,"height":1320},{"@type":"BreadcrumbList","@id":"https:\/\/menarah.org\/sirna-blocking-of-mammalian-target-of-rapamycin-mtor-attenuates-pathology-in-annonacin-induced-tauopathy-in-mice\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/menarah.org\/"},{"@type":"ListItem","position":2,"name":"siRNA blocking of mammalian target of rapamycin"}]},{"@type":"WebSite","@id":"https:\/\/menarah.org\/#website","url":"https:\/\/menarah.org\/","name":"\u0645\u0646\u0627\u0631\u0629","description":"\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0634\u0631\u0642 \u0627\u0644\u0623\u0648\u0633\u0637 \u0648\u0634\u0645\u0627\u0644 \u0623\u0641\u0631\u064a\u0642\u064a\u0627 \u062d\u0648\u0644 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0635\u062d\u064a\u0629","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/menarah.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ar"},{"@type":"Person","@id":"https:\/\/menarah.org\/#\/schema\/person\/31d8b4616fa7455ebb0b07916a647a77","name":"\u062f\u0643\u062a\u0648\u0631 \u0645\u062d\u0645\u062f \u0633\u0644\u0627\u0645\u0629","image":{"@type":"ImageObject","inLanguage":"ar","@id":"https:\/\/menarah.org\/wp-content\/uploads\/2020\/05\/M_Salama_photo-1.jpg","url":"https:\/\/menarah.org\/wp-content\/uploads\/2020\/05\/M_Salama_photo-1.jpg","contentUrl":"https:\/\/menarah.org\/wp-content\/uploads\/2020\/05\/M_Salama_photo-1.jpg","caption":"Dr. Mohamed Salama"},"description":"Institute of Global Health and Human Ecology,\u00a0American University in Cairo, Egypt Dr Mohamed Salama established the first Translational Neuroscience Unit in Egypt. Mohamed\u2019s collaborative research led to establishing the Egyptian Network for Neurodegenerative Disorders (ENND). Mohamed was selected as a SOT Global Senior Scholar in 2013 and Translational\/bridging awardee in 2016. He was awarded by Parkinson\u2019s and Movement Disorders Foundation (PMDF) for his continuing research in the field of neurodegeneration. Recently, Mohamed and his colleagues succeeded to draft the first Reference Egyptian Genome\u00a0and collaborating with other colleagues to start a national cohort (A Longitudinal Study of Egyptian Health Aging [AL-SEHA]).\u00a0Currently, Mohamed is Atlantic senior fellow for Equity in brain health at the Global Brain Health Institute (GBHI) and Associate professor at the Institute of Global Health and Human Ecology at the American University in Cairo (AUC).","url":"https:\/\/menarah.org\/ar\/author\/mohamedsalama\/"}]}},"featured_image_src":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12-600x400.png","featured_image_src_square":"https:\/\/menarah.org\/wp-content\/uploads\/2018\/10\/Screenshot-2020-06-24-at-15.29.12-600x600.png","author_info":{"display_name":"Dr. Mohamed Salama","author_link":"https:\/\/menarah.org\/ar\/author\/mohamedsalama\/"},"_links":{"self":[{"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/posts\/198","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/comments?post=198"}],"version-history":[{"count":1,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/posts\/198\/revisions"}],"predecessor-version":[{"id":1519,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/posts\/198\/revisions\/1519"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/media\/282"}],"wp:attachment":[{"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/media?parent=198"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/categories?post=198"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/menarah.org\/ar\/wp-json\/wp\/v2\/tags?post=198"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}